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Diclofenac is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis.
Active Ingredient: Diclofenac
Availability: In Stock (34 Packages)
What is Diclofenac?
Diclofenac is a drug with analgesic, antipyretic and anti-inflammatory effects.
Indications for use
Diclofenac has no effect on the progression of the disease, it is intended for symptomatic therapy, reduction of inflammation and severity of pain.
Diclofenac in the form of tablets and suppositories is prescribed for the following diseases / conditions:
- Pain syndrome in oncological diseases, dental and headache (including migraine) pain, sciatica, lumbago, sciatica, ossalgia, myalgia, neuralgia, arthralgia, as well as inflammation of postoperative and post-traumatic pain syndrome;
- Diseases of the musculoskeletal system (degenerative and inflammatory), including ankylosing spondylitis (ankylosing spondylitis), psoriatic, rheumatoid, juvenile chronic arthritis, gouty arthritis, osteoarthritis, tendovaginitis, bursitis;
- Inflammatory processes in the pelvis, including adnexitis; Algomenorrhea; Infectious and inflammatory diseases of upper respiratory tract, accompanied by severe pain, including tonsillitis, pharyngitis and otitis media (as part of complex treatment).
Contraindications to the use of Diclofenac in the form of tablets and suppositories are:
- The combination (incomplete or complete) of asthma and recurrent polyposis of the paranasal sinuses and nose with intolerance to acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs (including a history);
- Active gastrointestinal bleeding;
- Inflammatory bowel disease;
- Erosive and ulcerative lesions of the stomach and duodenum;
- Severe hepatic and renal failure (creatinine clearance less than 30 ml per minute);
- Progressive kidney disease;
- Active liver disease;
- Confirmed hyperkalemia;
- The period after coronary artery bypass surgery;
- Severe heart failure;
- The third trimester of pregnancy and lactation (in I-II trimesters of pregnancy, Diclofenac can be used in the lowest dosage and under strict indications);
- Children’s age: tablets – up to 6 years;
- Hypersensitivity to the components of the drug, as well as to other nonsteroidal anti-inflammatory drugs.
With prolonged use of Diclofenac, liver function, fecal occult blood analysis and peripheral blood picture should be monitored.
During the period of therapy, there may be a decrease in the speed of motor and mental reactions, in connection with which one should refrain from driving vehicles and performing other potentially dangerous types of work requiring high concentration of attention and quick psychomotor reactions.
How to use?
Diclofenac in the form of tablets should be taken orally, without chewing and drinking plenty of water, preferably 30 minutes before a meal (to achieve a rapid therapeutic effect). It is also possible to take the drug before, during or after a meal.
Children from 15 years and adults Diclofenac is prescribed 2-3 times a day, 25-50 mg (maximum – 150 mg per day). After improvement, the dose is gradually reduced and transferred to maintenance therapy – 50 mg per day.
When treating juvenile rheumatoid arthritis, the daily dose can be increased to 3 mg / kg body weight.
For children, the drug is usually prescribed in the following doses (single / daily):
- 6-7 years (20-24 kg) – 25/25 mg;
- 8-11 years (25-37 kg) – 25 / 50-75 mg;
- 12-14 years (38-50 kg) – 25-50 / 75-100 mg.
When using Diclofenac in the form of tablets, the following side effects may develop:
- Nervous system: often – dizziness, headache; rarely – sleep disturbances, depression, irritability, drowsiness, aseptic meningitis (more often in patients with systemic lupus erythematosus and other systemic diseases of the connective tissue), nightmares, convulsions, disorientation, general weakness, and a feeling of fear;
- Gastrointestinal tract: often – nausea, diarrhea, constipation, abdominal pain or spasm, abdominal distention, flatulence, peptic ulcer with possible complications, increased activity of “hepatic” transaminases, gastrointestinal bleeding without an ulcer; rarely – damage to the esophagus, vomiting, melena, jaundice, the appearance of blood in the feces, aphthous stomatitis, cholecystopancreatitis, hepatitis (perhaps fulminant course), dry mucous membranes (including the oral cavity), cirrhosis, hepatic necrosis, changes in appetite, hepatorenal syndrome, colitis, pancreatitis (including with concomitant hepatitis);
- Respiratory system: rarely – bronchospasm, cough, pneumonitis, laryngeal edema;
- Cardiovascular system: rarely – increased blood pressure; extrasystoles, congestive heart failure, chest pain;
- Urogenital system: often – fluid retention; rarely – oliguria, papillary necrosis, nephrotic syndrome, proteinuria, interstitial nephritis, hematuria, azotemia, acute renal failure;
- Skin: often – skin rash, pruritus; rarely – urticaria, alopecia, toxic dermatitis, eczema, punctate hemorrhages, toxic epidermal necrolysis (Lyell’s syndrome), erythema multiforme exudative (including Stevens-Johnson syndrome), increased photosensitivity;
- Sense organs: often – tinnitus; rarely – scotoma, diplopia, blurred vision, taste disturbance, irreversible or reversible decrease in hearing;
- Hematopoietic organs and immune system: rarely – anemia (including aplastic and hemolytic anemia), thrombocytopenia, leukopenia, agranulocytosis, eosinophilia, thrombocytopenic purpura, worsening of the flow of infectious processes;
- Allergic reactions: rarely – anaphylactoid reactions, allergic vasculitis, swelling of the tongue and lips, anaphylactic shock (usually develops rapidly).