Buy Metformin online without a doctor's prescription

metformin online
Metformin is a biguanide anti-diabetic that works by decreasing the amount of sugar that the liver produces and the intestines absorb.
Active Ingredient: Metformin
Availability: In Stock (32 Packages)
Metformin 850mg
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Metformin 500mg
Product name Per Pill Savings (only today) Per Pack
90 pills $0.37 $33.58 ADD TO CART
180 pills $0.30 $12.98 $67.15 $54.17 ADD TO CART
360 pills $0.26 $38.95 $134.31 $95.36 ADD TO CART

What is Metformin?

Metformin is an antidiabetic drug that promotes better glucose uptake. The World Health Organization has included this tool in the list of essential drugs. The drug belongs to the group of biguanides, the active substance dimethyl biguanide. Get it from the plant Galega officinalis. Metformin prevents the synthesis of glucose by the liver (the process of gluconeogenesis), thereby reducing blood sugar levels. In parallel with this, the drug increases the sensitivity of insulin receptors, improving its absorption, promotes better oxidation of fatty acids, increases peripheral glucose utilization, reduces its absorbability from the digestive tract. The tool helps to reduce thyroid-stimulating hormone in the blood serum, lowering the level of cholesterol and low-density lipoproteins, thereby preventing pathological changes in the blood vessels. Normalizes blood clotting, improving its rheological properties, thereby helping to reduce the risk of blood clots. Indication for use Metformin is indicated for the treatment of type 2 diabetes with preserved renal function, as well as a pre-diabetic condition. A direct indication for use is type 2 diabetes, accompanied by obesity. It is also used as part of complex therapy in the treatment of abdominal-visceral obesity. During use in clinical practice, reviews of Metformin were so positive that, after conducting confirming clinical studies, in 2007 the drug was recommended for use in pediatric practice for the treatment of type 1 diabetes, as a supplement to insulin therapy. Contraindications The instructions Metformin indicated the following contraindications:
  • Lactic acidosis, currently available or in history;
  • Precomatosis;
  • Hypersensitivity to any of the components of the drug;
  • Impaired renal function, as well as associated diseases that can cause such a violation;
  • Adrenal insufficiency;
  • Liver failure;
  • Diabetic foot;
  • All conditions that cause dehydration (vomiting, diarrhea) and hypoxia (shock, cardiopulmonary insufficiency);
  • Alcoholism. It is necessary to take into account that even a single combined use of Metformin and alcohol can cause a severe metabolic disorder;
  • Infectious diseases in the acute period, accompanied by fever;
  • Chronic diseases in the stage of decompensation;
  • Extensive surgery and postoperative rehabilitation;
  • Breast-feeding;
Pregnancy, like childhood, is no longer regarded as an absolute contraindication to taking the drug, since Metformin may be prescribed for the treatment of gestational and juvenile diabetes, but in these cases the therapy is strictly under medical supervision. Special instructions In monotherapy with Metformin, there is no risk of hypoglycemia, as part of the complex treatment of diabetes, such a risk is not excluded, which is necessary to warn the patient. Prohibited the joint intake of this drug and intravascular radiopaque substances containing iodine. Any combined use of Metformin and another medicinal substance requires the supervision of a physician. When conducting a surgical intervention, drug therapy is canceled for 2-3 days in the postoperative period. Instructions Metformin prescribes a diet during the entire period of treatment, which allows to avoid sharp peaks and drops in blood glucose, causing deterioration of health.

How to use?

Metformin tablets are taken strictly after meals, drinking plenty of water. The first and initial doses – 1000 mg per day, for 1-2 weeks the dose gradually increases, its value is adjusted under the control of laboratory data on the level of glucose in the blood. The maximum allowable dose is 3000 mg per day. The daily dose can be used at one time, but at the beginning of therapy, during the adaptation period, it is recommended to divide it into 2-3 doses, which helps to reduce the side effects of the drug on the gastrointestinal tract. The highest concentration of the drug in the blood plasma is noted 2.5 hours after administration, after 6 hours it begins to decrease. After 1-2 days of regular intake, a constant concentration of the drug in the blood is established, according to reviews Metformin begins to have a noticeable effect two weeks after the start of administration. When combined use of Metformin and insulin, medical observation is necessary, with high doses of insulin – in the hospital.

Side effects

When used according to the instructions Metformin is usually well tolerated by patients, rarely causing side effects. If there are any, then, as a rule, they are associated either with individual drug intolerance, or with interaction with other drugs, or with overdosing. According to reviews, Metformin most often causes disorders of the digestive system, manifested in the form of dyspepsia in one form or another, as one of the symptoms of lactic acidosis. Typically, such signs are observed at the beginning of the course of drug treatment, and after a period of adaptation pass. According to the instructions, Metformin in this case should be used in a reduced dosage, in case of severe lactic acidosis, the drug is canceled.
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