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Plaquenil (hydroxychloroquine) is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and lupus erythematosus.
Active Ingredient: Hydroxychloroquine
Availability: In Stock (32 Packages)
|Product name||Per Pill||Savings (only today)||Per Pack|
|10 pills||$4.03||$40.27||ADD TO CART|
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What is Plaquenil?
Plaquenil is an immunosuppressant used to treat malaria.
Plaquenil relieves inflammation, suppresses malaria pathogens, has a strong immunosuppressive effect (inhibits the activity of the immune system).
The active substance of the drug is hydroxychloroquine.
Indications for use
Plaquenil according to the instructions prescribed for juvenile and normal rheumatoid arthritis, systemic, discoid lupus erythematosus.
There are reviews of Plaquenil, successfully used for the treatment and prevention of acute attacks of malaria, provoked by such strains of Plasmodium: vivax, malariae, ovale, falciparum.
Plaquenil according to the instructions is contraindicated in case of hypersensitivity to hydroxychloroquine, lactating, pregnant women.
Long-term therapy with Plaquenil and drug analogues is contraindicated in children, since their active substance tends to accumulate in the body.
Patients with retinopathy who suffer from hematopoietic suppression in the bone marrow, psychosis, psoriasis, porphyria, renal or hepatic insufficiency, hepatitis, and glucose-6-phosphate dehydrogenase should be taken under supervision.
How to use?
Plaquenil is recommended to drink 200 ml of milk or taken with food.
The drug for rheumatoid arthritis in adults, incl. Elderly patients are prescribed at a dosage of 6.5 mg / kg, while for the calculation they take not the real, but the ideal weight. The maximum dosage allowed is 400 mg per day.
Plakenil is given to children, also counting on a dosage by weight – 6.5 mg per kilogram, but at the same time they take into account that children whose weight is less than 31 kg should not be given more than 200 mg of the drug.
In arthritis, Plaquenil can be combined with salicylates, nonsteroids, glucocorticosteroids, methotrexate, and their dosage can be reduced: the dosage of cortisone can be reduced by 5-15 mg; hydrocortisone dosage – 5-10 mg; triamcinolone or methylprednisolone – 1-2 mg; dexamethasone – 0.3-0.5 mg; Prednisone and Prednisolone – 1-2 mg.
With lupus erythematosus, adults give 400 mg of Plaquenil per day. The multiplicity of the use of funds – 1-2 times a day.
For the prevention of acute malarial seizures arising from the disease caused by Plasmodium malariae or falciparum strains, the drug is prescribed at a dosage of 400 mg. Take medication weekly, preferably on the same days of the week.
Children with malaria Plaquenil prescribed at a dosage of 6.5 mg / kg, but it is taken into account that the pediatric dosage can not exceed the adult.
Malaria prevention begins two weeks before entering the country, which is considered an endemic zone. If this is not possible, adults are prescribed a loading double dose of Plaquenil – 800 mg. In this case, children are given medicine at the rate of 12.9 mg / kg. Take a daily dosage in two doses with a break of 6 hours. After leaving the high-risk area for malaria, prophylaxis should be continued for another two months.
If an acute attack of malaria begins, adults give 800 mg of Plaquenil, after 6-8 hours – 400 mg, and another 400 mg of the drug – over the next two days.
There are good reviews about Plaquenil from patients taking a single 800 mg boosted dose during an acute malaria attack.
Children with an acute attack of malaria are given 32 mg of Plaquenil per kilogram of weight for three days.
Plaquenil and drug analogues can cause neuromyopathy and myopathy, headache, psychosis, convulsions, emotional lability, psychosis, hearing loss, accommodation disturbance, clouding or swelling of the cornea, tinnitus, retinopathy, blurred vision, keratopathy, optic nerve atrophy, AV blockade , myocardial hypertrophy, loss of appetite, aplastic or hemolytic anemia, abnormal liver function, vomiting, neutropenia, skin rash, abdominal pain.
There are reviews of Plaquenil from patients taking it, complaining of drug-induced alopecia, impaired skin pigmentation, itching, exacerbation of psoriasis, and increased photosensitivity of the skin.
With improper use of Plaquenil and overdose, side effects may increase. Excessive doses for children are especially dangerous – 1-2 g of medication can lead to death. Hydroxychloroquine poisoning is treated with gastric lavage, activated carbon, ammonium chloride, diuresis.